Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Adenoid Cystic Carcinoma
- Radiologic Findings
- Initial chest PA shows smooth narrowing of left main bronchus.
Chest CT shows enhancing homogeneous endobronchial mass involving carina to left main bronchus with marked narrowing of left main bronchus.
On bronchoscopy, endobronchial lesion appeared as a hypervascular submucosal mass nearly completely obstructing left main bronchus. Bronchoscopic biopsy was performed and was consistent with adenoid cystic carcinoma.
- Brief Review
- Adenoid cystic carcinoma generally occurs in the salivary glands. Pulmonary adenoid cystic carcinomas are rare, originating from submucosal glands of the airway and the majority developing in the lower trachea and mainstem bronchi. It is known to have no definite association with smoking and is prevalent in the 4th and 5th decade. Clinical manifestations are usually related to airway obstruction such as dyspnea, cough, stridor and wheezing.
On CT, adenoid cystic carcinoma appears as an intraluminal mass of soft tissue attenuation and has a tendency toward submucosal extension. The tumor may appear as a circumferential wall thickening, a homogeneous mass encircling the trachea or a soft tissue mass filling the airway. Longitudinal extent is usually greater than axial extent.
Adenoid cystic carcinoma is generally regarded as a slow growing, low grade malignancy, which has a tendency for local recurrence. Surgical resection should be performed whenever possible and in inoperable cases, radiotherapy and chemotherapy can be considered. Distant metastasis is usually absent until the late stage and metastasis to the lung is the most common.
- References
- 1. Kwak SH, Lee KS, Chung MJ et al. Adenoid Cystic Carcinoma of the Airways: Helical CT and Hisopathologic Correlation. AJR AM J Roentgenol. 2004;183:273-281
- Keywords
- Airway, Malignant tumor,